Molecular Formula | C14H28O6 |
Molar Mass | 292.37 |
Storage Condition | 2-8°C |
In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
bioactivity | m-PEG4-Boc is a cleavable ADC linker containing 4 units of PEG, it can be used to synthesize antibody-conjugated drugs (ADCS). m-PEG4-Boc is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules. |